The short answer
From 2025, new residential split systems using R-410A can't be manufactured or imported in the US. Makers moved to R-32 and R-454B, lower-global-warming A2L refrigerants. EPA's 2026 rule lets pre-2025 R-410A inventory still be installed; New York set its own, earlier installation deadline.
The three refrigerants
| Refrigerant | Global warming potential | Safety class |
|---|---|---|
| R-410A | 2,088 | A1 (non-flammable) |
| R-32 | 675 | A2L (mildly flammable) |
| R-454B | 466 | A2L (mildly flammable) |
What it means for you
- Line sets and line-set covers carry over; refrigerants don't mix, so a new system uses its own charge.
- A2L systems include leak detection or charge limits set by the maker and building codes.
- Service and parts for R-410A systems continue; recovered and reclaimed R-410A stays available.
- Compare systems on capacity, SEER2 and cold-weather heating; the refrigerant itself makes little difference to running cost.
Examples
The MRCOOL DIY 12,000 BTU is an R-410A system; the MRCOOL Easy Pro and Senville LETO use R-454B; the DELLA Vario 115V uses R-454B as well.
Products mentioned
Questions readers ask
Can I still buy an R-410A mini-split?
Yes, from existing inventory; EPA's 2026 rule allows pre-2025 R-410A equipment to be installed, except where states such as New York set their own deadline.
Is R-32 better than R-454B?
Both are A2L refrigerants with much lower warming potential than R-410A; differences in real-world efficiency are small, so compare the system's ratings instead.